Changes in bromsulfophtalein (BSP) retention rate in fattening pigs
2008
Oshida, T.(Azabu Univ., Sagamihara, Kanagawa (Japan). School of Veterinary Medicine) | Henzan, H. | Kitamura, H.
The Bromsulfophtalein (BSP) test for liver function has been widely conducted on human subjects and the results examined in detail. But this test has hardly at all been carried out on domestic animals such as the pig. Examination was thus made in the present study of BSP retention time over a period of 30 minutes in fattening pigs 1 to 6 months of age. Serum enzyme activity was determined as an index of liver function in relation to serum albumin content. The following results were obtained: 1. BSP retention time changed with physiological development during aging. This time increased by 2.5% at 1 month to 4.0% at 3 months and subsequently decreased to 2.5% at six months. 2. Retention time was seen to be related to serum enzyme activity and serum albumin content. In GPT, change in ALP and GOT occurred in a manner different from that noted for BSP retention time and no correlation could be detected. But change in GGT and serum albumin was observed to be similar to that in retention time and the two were seen significantly correlated. The equation for regression and the coefficient of correlation were determined as y=4.55x + 15.7 (r=0.643**) and y=0.25x + 2.94 (r=0.747**), respectively.
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