Feline digital phaeohyphomycosis due to Exophiala jeanselmei
2008
Maeda, H.(Nihon Univ., Fujisawa, Kanagawa (Japan). Coll. of Bioresource Sciences) | Shibuya, H. | Yamaguchi, Y. | Miyoshi, T. | Irie, M. | Sato, T.
The black nodule measuring 1 cm in diameter developed in the base of nail of an 8-year-old Japanese domestic male cat. Histological examination of the excised nodule revealed a granulomatous lesion extending from the epidermis to adjacent bone. The lesion was consisted of diffuse infiltration of macrophages with epithelioid cells and multinucleated giant cells. These macrophages contained a few to numerous yeast-like brown pigmented fungus cells with a spherical shape and dark thick wall. The PCR amplification with universal primers of the 28S ribosomal RNA gene yielded a 628-bp fragment and the direct sequence confirmed that the diagnosis of the lesion was phaeohyphomycosis caused by the pathogenic dematiaceous fungus, Exophiala jeanselmei.
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