Treatment with Lomustine for mediastinal lymphoma in a rabbit
2009
Onuma, M.(Onuma Animal Hospital, Koshigaya, Saitama (Japan)) | Kondo, H. | Ishikawa, M. | Ono, S. | Ueki, M. | Shibuya, H. | Sato, T.
A rabbit (Oryctolagus cuniculus) with leukemic mediastinal lymphoma, which had not responded to steroid therapy, received the alkylating agent Lomustine (50 mg/squarem) twice at 21-day intervals until complete remission was achieved. No serious side effects were encountered, other than a slight increase in serum ALP level. The rabbit died due to renal failure 91 days after the second administration of Lomustine. The survival time was 128 days in this case.
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