Antigenotoxic effect of plant extracts
2007
Knezevic-Vukcevic, J., University of Belgrade, Belgrade (Serbia). Faculty of Biology | Vukovic-Gacic, B., University of Belgrade, Belgrade (Serbia). Faculty of Biology | Simic, D., University of Belgrade, Belgrade (Serbia). Faculty of Biology
Antigenotoxic potential in this study is estimated with prokaryotic and eukaryotic tests measuring spontaneous and induced mutations, recombination, mutagenic repair, chromosomal aberrations and micronuclei. The results indicate that monoterpenoids from sage act as modulators of DNA repair pathways, whereas sage antioxidants interfere with metabolic activation enzymes. The potential use of sage extracts in cancer prevention is discussed.
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