Патогенез при экспериментальном эзофагостомозе свиней
2010
Sajko, A.L., Volkovysk State Agrarian College (Belarus)
In the conditions of the Republic of Belarus there was determined the parasitizing influence of Oesophagostomum and their larvae on a metabolism of experimentally infested animals. In course of the study there were generated experimental and control groups of two-month old piglets. Animals of the experimental group were infested in a dose of 15000 invasion larvae per one kg of body weight. Animals of the control group were not infested. Infestation was realized through a mouth with invasion larvae with wet forage. Invasion larvae received by cultivation of excrement tests from infested pigs at temperature of 24 deg C. As a result of the realized research it was established, that Oesophagostomum invasion rendered a substantial influence on the experimental animals. At bimestrious pigs after the experimental infection with Oesophagostomum larvae there were stated the following changes: the disease on 4-30th day was characterized by frustration of function of a gastroenteric path - diarrhea, fever, anaemia, and in the subsequent - stagnation and juvenilism of animals. Oesophagostomum in a host organism caused the pathological changes of haemotological and biochemical blood value which were expressed in quantity decrease of erythrocytes, concentration of haemoglobin, leucocytosis. Eosinophilia was observed in a leukogram. In blood serum there was stated the lowering of crude protein and its fractions content; gradually, but authentically there was noted the increasing of activity serum glutamic oxalacetic transaminase and glutamic-pyruvic transaminase. Bactericidal and lysozymic activity of blood serum decreased. Activity of alkaline phosphatase increased.
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