The antimicrobial susceptibility and virulence factors of Bacillus anthracis strains isolated in Croatia
2011
Habrun, B.,Croatian Veterinary Inst., Zagreb (Croatia) | Racic, I.,Croatian Veterinary Inst., Zagreb (Croatia) | Kompes, G.,Croatian Veterinary Inst., Zagreb (Croatia) | Spicic, S.,Croatian Veterinary Inst., Zagreb (Croatia) | Benic, M.,Croatian Veterinary Inst., Zagreb (Croatia) | Mihaljevic, Z.,Croatian Veterinary Inst., Zagreb (Croatia) | Cvetnic, Z.,Croatian Veterinary Inst., Zagreb (Croatia)
Bacillus anthracis can infect both livestock and humans. The presence of PA and B/C genes (pX01 and pX02 plasmids) as well as susceptibility to several antimicrobial substances was determined in 11 strains of Bacillus anthracis isolated during two recent epizooties of anthrax which occurred in Croatia in 2002 among sheep and in 2006/2007 in cattle. The pX01 plasmid was observed in all of the examined strains, including vaccinal Sterne strains. However, the pX02 plasmid was detected in only eight out of eleven examined field strains of Bacillus anthracis while in vaccinal strains it was not detected at all. Determination of MIC's revealed susceptibility to amoxicillin, amoxicillin with clavulanic acid, ciprofloxacin, gentamicin and tetracycline. All strains were resistant to sulfamethoxazole with trimethoprim and cefotaxime.
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