Skin UVB Photo Aging Effect from Extract of Fermented Reynoutria elliptica
2010
Lim, A.K., Daegu Technopark Bio Industry Center, Daegu, Republic of Korea | Jung, Y.J., Inje University, Gimhae, Republic of Korea | Kim, K.S., Kyungpook National University, Daegu, Republic of Korea | Kim, Y.H., Shinhwa Pharam Research Institute, Daegu, Republic of Korea | Kwak, J.H., Shinhwa Pharam Research Institute, Daegu, Republic of Korea | Hong, J.H., Catholic University of Daegu, Gyungsan, Republic of Korea | Kim, H.Y., Keimyung University, Daegu, Republic of Korea | Kim, D.I., Daegu Technopark Bio Industry Center, Daegu, Republic of Korea
To evaluate the skin aging inhibition effect of fermented Reynoutria elliptica, skin aging model was produced by the irradiation of UVB to hairless mice for 5 weeks. The skin erythema index for the positive control (PC), not fermented Reynoutria elliptica extract (NFR), and fermented Reynoutria elliptica extract (FR-500, 1000, 2000) groups were lower than that of the control group. However, both lipid and water capacity for the PC and FR groups were higher than those of the control group. Collagen fibers in dermis of the FR groups were almost intact with a regular arrangement which were similar to the normal (NO) group. Also, relatively much less number of mast cells and inflammatory cells were found in FR groups. The skin TBARS contents and XO activity in the FR group were significantly lower than the control group. The activities of GSH, SOD and CAT for the FR groups were significant higher than the control group. Therefore, fermented Reynoutria elliptica extract can be practically useful for the prevention or improvement of skin aging in terms of health promotion and beauty for the people.
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