The development of oxidative stress in different types of physical activities of racehorses | Razvoj oksidativnog stresa u različitim tipovima fizičkog opterećenja sportskih konja
2011
Jović, S., Fakultet veterinarske medicine, Beograd (Serbia) | Stevanović, J., Fakultet veterinarske medicine, Beograd (Serbia) | Trailović, D., Fakultet veterinarske medicine, Beograd (Serbia) | Valčić, O., Fakultet veterinarske medicine, Beograd (Serbia)
The horses predisposition for racing is inherited. Their great athletic capabilities are associated with their exceptional ability of adaption to increased physical activity. Throughout the training, the demands in loading and speed increase in accordance with the individual features of horses. Well-designed trainings result in increased aerobic capacity, enlargement of myocardium and skeletal muscle mass and better blood flow into these, with the aim of increasing the muscle strength, enhanced biomechanical abilities, neuromuscular coordination and motivation for race. Oxidative stress results from the imbalance between pro-oxidant and antioxidants. Physiological and non-physiological processes followed by the loss of control of ROS and RNS production and their synthesis in enormous amounts beyond the antioxidant capacity of cells and tissues lead to their oxidative damage. Enhanced oxidative metabolism, developing even during moderate physical activity, is followed by higher ROS production, which results in the damage of various cells and biomacromolecules. When activated, these disturbances are followed by chain various cells and biomaromolecules. When activated, these disturbances are followed by chain oxidative reaction, which may result in degenerative changes and the occurrence of various ailments.
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