Toxic effects of pesticides: a review on cytogenetic biomonitoring studies
2008
Palani Kumar, L., The Madura College, Madurai (India). Research Centre and Post Graduate Studies in Botany | Panneerselvam, N., The Madura College, Madurai (India). Research Centre and Post Graduate Studies in Botany
Pesticides constitute a heterogeneous category of chemicals specifically designed for the control of pests, weeds or plant diseases. Biological monitoring provides a useful tool to estimate the genetic risk deriving from an integrated exposure to a complex mixture of chemicals. Studies available in scientific literature have essentially focused on cytogenetic end-points to evaluate the potential genotoxicity of pesticides in occupationally exposed populations. A positive association between occupational exposure to complex pesticide mixtures and the presence of chromosomal aberrations (CA), sister-chromatid exchanges (SCE) and micronuclei (MN) has been detected in the majority of the studies. Genetic damage associated with pesticides occurs in human populations subject to high exposure levels due to intensive use, misuse or failure of control measures.
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