In Vivo Determination of the Complex Elastic Moduli of Cetacean Head Tissue
2009
Rogers, Peter H. | Martin, James S. | Gray, Michael D.
A confocal ultrasonic elastography system was designed, developed, and tested with discrete scatterers and tissue phantoms. The former experiments demonstrated the ability to use ultrasound for remote generation and detection of vibrations in the audio frequency range. The latter experiments demonstrated the ability to remotely detect shear wave motion amplitude and phase as a function of depth along the ultrasonic beam and determine the wave propagation speed. Results from these tests were in good agreement with results obtained from a resident dynamic mechanical testing facility. Considerable effort was applied towards refining the detection system hardware and signal processing in order to improve overall measurement quality and reduce noise, with the ultimate goal of reducing ultrasonic drive level requirements. System simulation models were developed to assist the vibration measurement algorithm development effort. Work performed under this grant has set the stage for testing on tursiops truncatus tissue samples and live animals in FY09 under a follow-on grant.
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