Total Synthesis of Paecilospirone.

Yuen, TY; Yang, SH; Brimble, MA

Total Synthesis of Paecilospirone.

2011

Yuen, TY | Yang, SH | Brimble, MA

In 2000, Namikoshi et al. reported the isolation and structuralelucidation of a novel [5,6]-bisbenzannulated spiroacetal[1]from the marine fungus Paecilomyces sp.[2]This uniquespiro[chroman-2,1’(3’H)-isobenzofuran] derivative was identified as a potential antimitotic agent (20 % inhibition at50 mm) using an assay screening for microtubule assemblyinhibitors and was subsequently named paecilospirone (1).

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anglais

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Angew Chem Int Ed EnglItems in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/1433-7851/https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htmCopyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheimhttp://purl.org/eprint/accessRights/RestrictedAccess

ISSN

8350-8353, 1521-3773, 1433-7851

Type

Journal Article; Journal Part

Source

Sur AGRIS depuis: 2013-06-15

Format: AGRIS AP

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