Comparison of Volatile Compounds of Chamaecyparis obtusa Essential Oil and its Application on the Improvement of Atopic Dermatitis

Lim, G.S., Chonnam National University, Gwangju, Republic of Korea; Kim, R., Wonkwang health science University, Jeonbuk, Republic of Korea; Cho, H., Chsun University, Gwangju, Republic of Korea; Moon, Y.S., Chsun University, Gwangju, Republic of Korea; Cho, C.N., Chonnam National University, Gwangju, Republic of Korea

Comparison of Volatile Compounds of Chamaecyparis obtusa Essential Oil and its Application on the Improvement of Atopic Dermatitis

2013

Lim, G.S., Chonnam National University, Gwangju, Republic of Korea | Kim, R., Wonkwang health science University, Jeonbuk, Republic of Korea | Cho, H., Chsun University, Gwangju, Republic of Korea | Moon, Y.S., Chsun University, Gwangju, Republic of Korea | Cho, C.N., Chonnam National University, Gwangju, Republic of Korea

Volatile flavor compounds of Chamaecyparis obtuse essential oil were extracted by simultaneous steam distillation extraction and supercrtical fluid extraction and analyzed by GC-MS. A total of 48 of and 50 components were identified in essential oil by SDE and SFE, respectively. Monoterpenes, oxygenated monoterpenes, sesquiterpenes, oxygenated sesquiterpense, and diterpenes in essential oil by SDE were 37.24, 10.9, 9.61, 0.22, and 0.22 % , respectively . In the case of SFE, they were 19.1, 23.3, 22.66, 1.31, and 10.57%, respectively. Antioxidant activities were increased with the increase of essential oil up to 80 mL/mL. irrespective of extraction method . Especially, when the essential oil concentraion extracted by SDE was increased from 20 to 80ml?ml. the antioxidant activity was increased from 10.5 to 55.1%, However, over 80ml/ml of essential oil, an equilibrium state was maintained . In the case of essential oil extracted by SFE, it was decreased compared to that of SDE. For the improvement of atopic dermatitis, Various cosmetics such as an ato-cide soap, ato-cide spray, and ato-lotion containing essential oil extracted by SFE were tested. About over 90% was useful for the improvement of atopic dermatitis after 4 week of clinical trail targeting 40 adults. These results demonsteate that ato-cide soap, ato- cide spray, and ato-cide lotion containing essential oil extracted by SFE could by used in functional cosmetics.

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