Analysis and Risk Assessment of Aflatoxin M1 in Infant Formula
2013
Kang, Y.W., Ministry of Food and Safety, Republic of Korea | Song, J.E., Ministry of Food and Safety, Republic of Korea | Suh, J.H., Ministry of Food and Safety, Republic of Korea | Park, S.K., Ministry of Food and Safety, Republic of Korea | Kim, M.J., Ministry of Food and Safety, Republic of Korea
To analyze aflatoxin M1 (AFM1), we dissolved infant formula in warm water and cleaned it by using an immunoaffinity column (IAC). The amount of AFM1 was determined by high-performance liquid chromatography coupled with fluorescence detection. AFM1 was detected in 281 of 439 samples. Thus, the detection rate of AFM1 was 64.0%. The average concentration of AFM1 in positive samples was 2.6 ng/kg (of prepared formula). The estimated daily intake (EDI) of AFM1 through infant formula was 0.087-0.646 ng/kg body weight/day and the additional number of cases of liver cancer associated with exposure to AFM1 would be 0.003-0.020 cancer cases/1,000,000. Because there is less than 1 cancer case/ 1,000,000 per year, the exposure to AFM1 through infant formula in Korea is considered to be an unlikely human health concern.
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