Anti-oxidative Effect of Oyster Hydrolysate on the Serum and Hepatic Homogenate in SD-rats
2013
Hur, S.I., Gyeongsang National University, Gyeongnam, Republic of Korea | Park, S.H., Sun Marine Biotech Co., Gyeongnam, Republic of Korea | Lee, S.S., Sun Marine Biotech Co., Gyeongnam, Republic of Korea | Choung, S.Y., Kyung Hee University, Seoul, Republic of Korea | Choi, Y.J., Gyeongsang National University, Gyeongnam, Republic of Korea
This study is conducted to investigate the antioxidative effect of oyster hydrolysates in the serum and liver of SD-rats through the determination of lipid content, production of free radicals and antioxidant enzyme activities. Two different hydrolysates, Protamex-treated and Neutrase-treated hydrolysate with the cross-linking of protein by transglutaminase (TGPN group) and without (PN group), were fed for 6 weeks. TGPN hydrolysate in serum and liver significantly decreased the total cholesterol in the range of 26.1% to 28.9%, and triglyceride in the liver of up to 6.3%. Superoxide radical in the serum and lipid peroxide radical in the liver were significantly decreased in SD-rats fed 200 mg TGPN hydrolysate. Superoxide dismutase activity was significantly decreased in the liver of SD-rats. These results indicate that TGPN hydrolysate could scavenge the superoxide and hydroxyl radicals, and reduce the superoxide dismutase and catalase activities. The TGPN is also protected the oxidation of protein by the free radicals.
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