Blood pressure and aortic lumen diameter changes after replacing aorta abdominalis with prosthesis
2013
Malniece, A., Latvia Univ. of Agriculture, Jelgava (Latvia) | Auzans, A., Latvia Univ. of Agriculture, Jelgava (Latvia) | Drevinska, K., Latvia Univ. of Agriculture, Jelgava (Latvia)
The objective of this study was to observe and evaluate the ability of innovative vascular prosthesis, made in Riga Technical University (RTU), to incorporate in a canine model. The research has been performed in Veterinary Medicine Faculty of Latvia University of Agriculture since July 19. 2011. The research was approved by the Food and Veterinary Service of the Republic of Latvia. The research is realized within the framework of European Social Fund co-financed project ‘Establishment of interdisciplinary research groups for new functional properties of smart textiles development and integrating in innovative products’ (ESF No 2009/0198/1DP/1.1.1.2.0./09/APIA/VIAA/148). RTU produced aortic grafts 5-8 mm in diameter and 8 mm to 18 mm long were implanted retroperitoneal in 9 female, 1-3 years old Beagle dogs. Once before and regularly after the surgery, abdominal aortic and vascular graft diameter was measured in cross sections. Blood pressure was measured before and regularly after the procedure. Results show no significant differences in aortic and graft diameter before and 12 months after the operation and there are no significant differences in systolic and diastolic blood pressure before and 6 months after the aortic surgery at a significance level α 0.05. The study shows that the innovative aortic prostheses do not change in diameter and abdominal aorta transplantation surgery does not cause significant variations in blood pressure. Study is continued to find out later reactions to synthetic vascular graft.
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