The influence of xenogenic mesenchymal stem cells on indicators of cellular immunity after systemically administration for recipient animals
2015
Mazurkevych, A.; Malyuk, M.; Kharkevych, Y; Savchuk, T.
Researched the indicators of absolute number of leukocytes and their subpopulations in the blood of rabbits and immunoregulatory index after administrating into their blood stream of xenogenic mesenchymal stem cells. Established that xenogenic mesenchymal stem cells do not possess immunogenic properties and show short-lived immunosuppressive effect, manifested in reducing of the absolute number of leukocytes and their subpopulations in their blood on the 3rd day of the experiment. Immunosuppressive effect of xenogenic mesenchymal stem cells vivo is most pronounced on the population of B-lymphocytes. Immunoregulatory index after administratingin vivo of xenogenic mesenchymal stem cells increases
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