Bioactive constituents from lichens
2016
Kosanić, Marijana (Faculty of Science, Kragujevac (Serbia). Department of Biology and Ecology) | Ranković, Branislav (Faculty of Science, Kragujevac (Serbia). Department of Biology and Ecology) | Ristić, Svetlana (Faculty of Science, Kragujevac (Serbia). Department of Biology and Ecology) | Manojlović, Nedeljko (Faculty of Medicinal Sciences, Kragujevac (Serbia). Department of Pharmacy)
Here we investigate antioxidant and antimicrobial activities of the acetone extract of the Cladonia rangiferina and their fumarprotocetraric acid. Antioxidant activity was evaluated by free radical scavenging, superoxide anion radical scavenging, reducing power and determination of total phenolics. As a result, fumarprotocetraric acid had larger free radical scavenging activity with (IC50 = 228.46 μg/mL). Tested samples also had effective reducing power and superoxide anion radical scavenging. Total phenolic content was determined as pyrocatechol equivalent. The antimicrobial activity was estimated by determination of the MIC, where most active was fumarprotocetraric acid with MIC values ranging from 0.03 to 0.25 μg/mL.
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