An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds
D. Craig | M. L. Marin
A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is reported. By means of an intramolecular Diels-Alder reaction an asymmetric approach to this ring has been accomplished. Also, initial studies to prepare the A ring using an intramolecular Diels-Alder reaction have been successful.
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