Production of natural rubber latex gloves with low extractable protein content: some practical recommendations
1994
Ng, K. P. | Yip, Esah | Mok, K. L.
With the reported incidence of Type 1 hypersensitivity associated with the presence of residual water-soluble proteins in latex, products, there is an urgent need to produce latex gloves with minimum extractable proteins. The + current practice of wet gel leaching for a short period of time is inadequate in reducing the extractable proteins. This study shows that an additional leaching operation after drying is necessary. The most effective means is the use of a re-centrifuged + prevulcanised latex with a combination of wet gel leaching and dry-film leaching or direct water spraying. Under the most favourable conditions, an extractable protein content of approximately 0.03 mg/g can be achieved. Physical properties of the low + extractable protein gloves are found to meet the requirements of ASTM D-3578-91 for natural rubber examination gloves. Their allergic response, as tested clinically on latex-sensitive patients by a skin-prick test, is found to be highly negative.
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