Latex allergy studies: B-serum from the latex bottom fraction as a major source of immunogenic glove proteins
1993
Sunderasan, E. | Yeang, H. Y.
A study was carried out to elucidate the source of potential allergenic proteins in fresh Hevea latex that are retained through the glove manufacturing process and appear in the finished product. By identifying the proteins of various latex component(s) that are responsible for the allergenicity, it might he possible to eliminate, or at least greatly reduce, these proteins at source. The origin of the potential allergens were traced by interacting latex proteins derived from Hevea latex C-serum, B-serum, rubber particle membranes and leaves with antibodies raised in rabbits against latex glove proteins. The strongest antigenic responses to the antibodies were from the B-serum proteins which arise from the lutoids, the main constituents of the latex bottom fraction.
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