DEPENDENCE OF ANTHELMINTIC EFFICACY ON PLANT COMPOSITION

In our studies, the method of helminthological autopsy was used to determine the anthelmintic efficacy of garlic, wormwood, licorice, harmala, camel thorn and ephedra. We conducted experiments on 42 sheep, collected in 7 groups, consisting of 6 experimental, 1 control group. We divided the animals into groups depending on the degree of infection with helminths, on weight and age. Therefore, after determining the infection with helminths of the studied animals by helminthoscopic methods, we divided them into groups. For 2 days, each group I sheep naturally infected with gastrointestinal nematodes was given 150 g of garlic juice mixed with water. Animals of group II were fed 150 g of wormwood for 3 days. For 3 days in a row, the sheep of group III were given 250 g of licorice. The helminth-infected sheep of the IV group were given 150 g of harmala with compound feed for 3 days. We fed animals of group V with 250 g of camel thorn for 5 days, and animals of group VI with 200 g of ephedra for 3 days. We also mixed ephedra with feed. Sheep infected with group VII helminths were kept under normal conditions and were not fed with anthelmintic plants. After 3 days of feeding with anthelmintic plants, the experimental animals and control groups were slaughtered and helminthological autopsy was performed. We collected Haemonchus, Strongylates and Trichucephaluses localized in the abomasum, small and large intestines of sheep and fixed them in Barbagol's solution in groups. In animals treated with garlic juice, anthelmintic efficacy against haemonchus was 84.9%, against strongylates 86.3%, against trichocephalus 52.7%. Compared with the control group, the effectiveness of wormwood against haemonchus reached 81.5%, and the severity of anthelmintic efficacy against strongylates and trichocephalus - 81.8 and 48.7%, respectively. Intensive effectiveness of licorice against haemonchus was 79.3%, anthelmintic efficacy against strongylates 77.1%, against trichocephalus 40.1%. The anthelmintic efficacy of harmala in the phase of fruit ripening reached 85.7% against haemonhus, against strongylates 84.3%, against trichocephalus 47.6%. Camel thorn, included in the animal feed base, gave 74.5% efficiency in hemonchosis, 72.4% in strongylatoses, and 40.1% in trichuriasis. The effectiveness of the intensity of ephedra against haemonchus was 80.6%, against strongylates 81.7%, against trichocephalus 50.3%.