Multivariate chemogenomic screening prioritizes new macrofilaricidal leads
2023
Nicolas J. Wheeler | Kaetlyn T. Ryan | Kendra J. Gallo | Clair R. Henthorn | Spencer S. Ericksen | John D. Chan | Mostafa Zamanian
A comprehensive optimization of phenotypic and computational screening strategy for antifilarial drug and target discovery identifies compounds with stage, species, and/or sex-specific activity, some with submicromolar potency.
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