Interaction kinetics between p115-RhoGEF and Gα13 are determined by unique molecular interactions affecting agonist sensitivity
2022
Fabian Redlin | Anna-Lena Krett | Moritz Bünemann
The three RH-RhoGEFs differ in their sensitivity of activation by G proteins. For p115-RhoGEF, a specific molecular interaction with Gα13 is responsible for faster kinetics and lower sensitivity.
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