Pathological and microbiological features and attempts to prevent chronic gastritis in pigs
1988
Baba, A.I. | Rapuntean, G. | Ghergariu, S. | Rotaru, O. | Spinu, O. | Voicu, O.
10 Landrace x Marele alb pigs weighing 23.5-33 kg were divided into 3 groups, treated with Ivomec and submitted to the following treatments: group 1 (3 pigs) which served as control, received daily 1 placebo tablet; group 2 (3 pigs) received daily 1 tablet Ulcosilvanil (1 tablet contains Acetazolamide 0,4 g; Potassium bicarbonate 0,140 g; Sodium bicarbonate 0,050 g; Sodium citrate 0,150 g; Magnesium oxide 0,180 g; aluminium hydroxide 0,080 g and excipient) for 30 days, followed by a pause of 30 days, and another period of 30 days with daily application of Ulcosilvanil; and group 3 (4 pigs) which received daily 1 tablet of Ulcosilvanil for 122 days. The pigs were weighed monthly and by the end of the experiment, they were subjected to euthanasy. Samples were drawn from several organs: gastric mucosa (cardia, fundus and pylorus); liver, kidney, adrenals and thyroid. The pigs from the group 2 had the highest daily weight gain as compared to the control, as well as minimal alterations of the gastric mucosa (mean lesional score = 1,25; group 3 = 1,66 and control 2,33). The main lesions of the gastric mucosa consisted in its thickening, conjunctival proliferation and lymphohistiocytic infiltrations. In all the groups tested spiral-shape Campylobacter-like microorganisms were found in the cardial and pyloric mucosa. It is concluded that the Ulcosilvanil exerts a beneficial effect on the integrity of the gastric mucosa, on the appetite and the daily weight gain in pigs. The possible involvement of the Campylobacter-like organism in the pathogenesis of the chronic gastritis may be presumed
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