The effects of the Czechoslovak developmental herbicide bentazone on some parameters of sheep health under the conditions of subchronic intoxication
1992
Neuschl, J. | Kacmar, P. | Legath, J. | Tomas, J. (Vysoka Skola Veterinarska, Kosice (CSFR))
A three-month feeding trial was conducted with sheep of the Slovak Merino breed (13-14 months of age, males and females) as a part of the obligatory toxicological tests of the Czechoslovak developmental herbicide bentazone (Research Institute for Chemical Technology, Bratislava). The sheep of the first experimental group were fed bentazone as an additive to molasses feed M at a daily rate of 195 mg/kg lwt. (1/10 of LD50), and the sheep of the second group were fed a rate of 97.5 mg/kg lwt. (1/20 of LD50). No symptoms of the toxic effects of bentazone were observed in the course of the experiment. There were no differences between the experimental and test animals in the dynamics of pulse value changes, breathing value changes and body temperature value changes from the beginning till the end of the trial. Neither were there any differences in the dynamics of liveweight changes. The animals of the 1st and control group had the same weight gains. Somewhat lower weight gains against the control were recorded in the 2nd experimental group. Since the target herbicide did not cause a growth depression, nor intoxication symptoms manifested in the breathing system and through body temperature changes (the dominant symptoms of acute intoxication), and in spite of the long-time administration of bentazone at high rates, this herbicide appears as a toxicologically reliable herbicide for sheep. Its nontoxic action is also illustrated by the fact that the continual rate of 97.5 mg/kg lwt. did not influence negatively the intrauterine foetus development in the last month of pregnancy, and the residues in milk did not influence the postnatal development of lambs.
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