The effect of repeated applications of GnRH (Dirigestran inj.) and follicotropine on concentrations of cholesterol, total lipids and progesterone in ewes during puerperium
1995
Krajnicakova, M. | Bekeova, E. | Maracek, I. | Hendrichovsky, V. (Ustav Experimentalnej Veterinarnej Mediciny, Kosice (Slovak Republic))
We investigated the effect of repeated application of synthetic GnRH and follicle-stimulating hormone on concentrations of cholesterol, total lipids and progesterone in blood plasma of lambing ewes in the puerperal period. To group 1 the first dose was applied 24 hours post partum (p.p.) and the second one 72 hours p.p. The experimental group 2 was treated with FSH at intervals of 24 and 72 h p.p. Blood samples were taken 36 h p.p. and on days 4, 7, 14, 17, 21, 25, 34 and 42 post partum. The experimental group cholesterol concentrations ranged from 1.56+/- 0.27 to 2.10 +/- 0.53 mmol/l, in experimental group 1 and from 1.51 +/- 0.12 to 1.91 +/- 0.28 mmol/l in group 2. Lipid concentrations in experimental group 1 ranged from 1.65 +/- 0.49 to 2.10 +/- 0.43 g/l and from 1.22 +/- 0.16 to 1.82 +/- 0.44 g/l in group 2. As for progesterone concentrations in the control group of lambing ewes, its episodic increase was recorded on day 34 p.p. together with a wide variance of individual values. In the experimental group treated with GnRH the highest P4 concentrations were obtained at 36th hour p.p. (0.7 +/- 0.2) and on day 14 (0.7 +/- 0.6 nmol/l). P4 concentrations on the FSH treated group did not exceed the values of 0.05 nmol/l of serum.
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