Assessment of the potential toxicity of an anticoagulant, pindone (2-pivalyl-1, 3-indandione), to some Australian birds
1994
Martin, G.R. | Kirkpatrick, W.E. | King, D.R. (Western Australian Dept. of Agriculture, Forrestfield. Agriculture Protection Board) | Robertson, I.D. | Hood, P.J. (Murdoch Univ. (Australia). School of Veterinary Studies) | Sutherland, J.R. (Texas A and M Univ., Armarillo (USA))
There was a need for an alternative poison that was highly toxic to rabbits but that posed a low risk to domestic stock. The sensitivity of a number of avian species to the rabbit poison pindone was investigated using increase of prothrombin time (PT) as an index of poisoning. Daily dose levels of pindone were 0.25 mg per kg for eagles, 4.0 mg per kg for magpies and 5.0 mg per kg for pigeons, parrots and ducks. Considerable species variation in response was observed, and within each species there was considerable individual variation in response to pindone. The PTs of magpies and ducks increased to approximately twice baseline levels. Significant elevations (4- to 7-fold) occurred in parrots, pigeons and eagles. Clinical symptoms were observed in only one species, the wedge-tailed eagle. Results of the dosing trials indicate that all species tested are theoretically at risk of pindone poisoning, although the risk to some species is minimised by factors such as population size, food availability and bait placement.
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