ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF A SERIES OF AROMATIC NITRONES | ACTIVITÉ ANTIMICROBIENNE ET ANTIOXYDANTE D’UNE SÉRIE DE NITRONES AROMATIQUE
2018
Kahina, HAMZA | Abdelkader, TOUATI | Atika, MEKLAT | Ahmed, AIT YAHIA | Noureddine, BOURAS | Michel, BALTAS | Saâd, MOULAY
Microbiological testsofa series of nitrones were performedby measuring the minimum inhibitory concentration (MIC) on sixteen targetedmicroorganisms.The results obtained showed that these compounds exhibitedgood antimicrobial activity and that this activitywasdependent on thesubstituent onthe aryl group of the nitrone.The addition of a surfactant was found toenhance thisactivity. In addition, the antioxidant activity tests of these nitroneswas assessedusing three chemical tests: 2,2-diphenyl-1-picrylhydrazyl (DPPH)free radical, β-carotene bleaching,and "ferric reducing antioxidantpower" (FRAP)method. The tests showedthat these compounds exhibitedan antioxidant capacity similar or better than α-phenyl-N-tert-butylnitrone (PBN) which was used asa reference.
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