Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton
2022
Mulyadi, T. | Tjitjik, S.T. | Shola, M. | Ghinsha, Z.R. | Muhammad, F.A. | Ratih, D.S. | Norizan, A.
Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM.
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