Tandem synthesis of substituted 2,7-naphthyridin-1(7H)-ones via Reissert reaction/intramolecular nucleophilic addition/oxidation dehydrogenation
2013
Tan, Hailiang | Wang, Jie | Zhang, Yu | Xing, Yongning | Sun, Qi | Li, Runtao
A convenient method for the synthesis of substituted 2,7-naphthyridin-1(7H)-ones has been developed. This method was carried out starting from a simple nicotinamide salts via a tandem process including Reissert reaction, intramolecular nucleophilic addition and oxidation dehydrogenation. Using this method, a variety of substituted 2,7-naphthyridin-1(7H)-ones were obtained in good yields.
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