Highly selective multifunctional nanohybrid catalysts for the one-pot synthesis of α,β-epoxy-chalcones
2016
Crivoi, Dana-Georgiana | Segarra, Anna M. | Medina, Francesc
An efficient one-pot heterogeneous process for producing chiral α,β-epoxy-chalcones from the corresponding aldehydes and ketones has been described. The nanohybrid materials based on poly-l-leucine immobilised into rehydrated hydrotalcites did not require any pre-activation and were easily recovered and recycled for four consecutive runs without losing their catalytic efficiency in terms of conversion, total selectivity towards the corresponding epoxy-chalcones and excellent enantioselectivity.
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