Aspergillosis of Biliary Tract After Liver Transplantation: A Case Report

Yuchong, Chen; Dingheng, Zhu; Zhizhong, Yuan; Hongyu, Yu; Jing, He; Jianghan, Chen

Aspergillosis of Biliary Tract After Liver Transplantation: A Case Report

2010

We reported a case of aspergillosis presented as cholangitis in a patient after liver transplantation, even with prophylactic use of fluconazole. The patient had multiple predisposing factors, such as leukocytopenia, immunosuppressive drug therapy. He died 2 days after an exploratory laparotomy was carried out. The histopathologic finding of biopsy specimen from biliary tract was positive for Aspergillus. And the pathogen was identified as Aspergillus flavus by mycological culture and PCR. The patient was confirmed as a case of Aspergillosis of biliary tract that was responded poorly to fluconazole. This indicated that azole should have been switched to more effective antifungal agents at earlier stage when the patients responded poorly to the original treatment.

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Mots clés AGROVOC

aspergillosis aspergillosis aspergillus flavus diagnosis drug resistance genetics humans leukopenia methods microbiology microscopy pathology

Informations bibliographiques

Publié dans

Mycopathologia

Volume 170 Numéro 2 Pagination 117 - 121 ISSN 0301-486X

Editeur

Blackwell Science

D'autres materias

Organ transplantation; Therapeutic use; Fluconazole; Liver transplantation; Middle aged; Isolation & purification; Adverse effects; Biliary tract; Male; Chemoprevention; Fatal outcome; Biliary tract; Histocytochemistry; Immunocompromised host; Fungal; Growth & development

Langue

anglais

Type

Text; Journal Article

Sur AGRIS depuis: 2024-02-27

Format: MODS

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Cette notice bibliographique a été fournie par National Agricultural Library

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Liens

DOI http://dx.doi.org/10.1007/s11046-010-9300-y

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