Copper-catalyzed C–H acyloxylation of 2-phenylpyridine using oxygen as the oxidant
2018
Wang, Feifan | Lin, Zhiyang | Yu, Weisheng | Hu, Qingdong | Shu, Chao | Zhang, Wu
An efficient copper-catalyzed direct o-acyloxylation of 2-phenylpyridine with carboxylic acids using oxygen as the oxidant has been developed. Various acids including aromatic acids, cinnamic acids and aliphatic acids are effective acyloxylation reagents and provide the desired products in moderate to excellent yields. The reaction proceeds well under an oxygen atmosphere, making this method potentially practical.
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