The synthesis of amino acid derived glycoconjugates and the investigation of their anti-inflammatory and analgesic properties
2014
Soni, Kiran | Sah, Ajay K.
A series of 4,6-O-ethylidene-β-d-glucopyranosylamine derived glycoconjugates containing amino- and aromatic acids have been synthesized. All these molecules have been tested for their anti-inflammatory and analgesic activity on Wistar rat and Swiss Albino mice respectively. The anti-inflammatory studies were explored using a carrageenan induced paw oedema model while an acetic acid induced writhing model was adapted for the analgesic studies. All of the compounds exhibited anti-inflammatory and analgesic activity in the range of 63–84% and 86–94% respectively.
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