Development of 2,4-diaminopyrimidine derivatives as novel SNSR4 antagonists
2011
Bayrakdarian, Malken | Butterworth, Joanne | Hu, Yun-Jin | Santhakumar, Vijayaratnam | Tomaszewski, Mirosław J.
2,4-Diaminopyrimidines derivatives were developed as a novel class of SNSR4 antagonists. Structure activity relationship of the diamino pyrimidine core was explored and a tool compound suitable for target validation was identified.
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