Parallel synthesis of bis-oxazole peptidomimetics
2013
Murru, Siva | Dooley, Colette T. | Nefzi, Adel
The parallel synthesis of bis-oxazole peptidomimetics starting from Boc-aminoacids and Serine-methyl ester is described. This work presents the synthesis of oxazole aminoacid building blocks in solution phase and their utilization for the solid phase peptide synthesis of a library of diverse bis-oxazole peptidomimetics in good overall yields.
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