A Study on the Mannich Reaction with 1-Phenylamino-3-indenone
2014
Hammouda, M. | Hamama, W. S. | Afsah, E. M.
Mannich reaction of the title compound 1 with formaldehyde and morpholine, piperidine or piperazine afforded the Mannich bases 3-5 respectively, whereas the indeno[1.2-d]pyrimidines (6-7) were obtained where primary amines were used. Treatment of 2 with formaldehyde gave benz[b]indeno-diazepine (8). The reaction of formaldehyde with 1 was also investigated.
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