Urea synthesis in rats fed diet containing kidney beans
1992
Scislowski, P.W.D. | Grant, G. | Harris, I. | Pickard, K. | Pusztai, A.
When rats were fed a diet containing kidney bean (Phaseolus vulgaris) urea excretion was increased 3-5 fold. Isolated liver mitochondria from rats fed the kidney bean diet produced 40% more citrulline in the presence of arginine than mitochondria isolated from control rats. Mitochondrial activities of urea cycle enzymes and N-acetylglutamate synthetase were similar in animals fed diets containing kidney bean or lactalbumin. The possible mechanisms causing acute urea production in rats fed with kidney bean are discussed.
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