IFITMs Restrict the Replication of Multiple Pathogenic Viruses
2013
Perreira, Jill M. | Chin, Christopher R. | Feeley, Eric M. | Brass, Abraham L.
The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis.
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