Microglia extracellular traps in Oreochromis niloticus infected with Weissella cibaria
2021
Eto, Silas F. | Fernandes, Dayanne C. | Funnicelli, Michelli I.G. | Alecrim, João V.C. | Souza, Pedro G. | Carvalho, Fabíola C.A. | Belo, Marco A.A. | Pizauro, João M.
The mechanism of extracellular traps (ETs) is important in the cellular response against bacteria. Thus, in the present study, we describe for the first time the capacity of the Nile tilapia (Oreochromis niloticus) microglia in the formation of ETs in Weissella cibaria in vitro infection. Thus, we evaluated the ultrastructure of the microglia culture and observed the formation of ETs 6 h after stimulation with lipopolysaccharide (LPS) and during the course of infection. Our results shed light on the mechanism of formation of ETs in the microglia of teleost fish and the ability of W. cibaria to infect these cells.
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