Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions
2017
Day, Rachael A. | Estabrook, Daniel A. | Logan, Jessica K. | Sletten, Ellen M.
Photodynamic therapy (PDT) requires a photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and a photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT.
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