Role of cAMP in Tissues of Mussel Mytilus galloprovincialis As a Potent Biomarker of Cadmium in Marine Environments
2007
Dailianis, Stefanos | Kaloyianni, Martha
The present study investigated the signal transduction molecule cAMP as a biomarker of exposure to cadmium in mussels Mytilus galloprovincialis. Mussels were exposed to 10 and 100 μg/l cadmium for 3, 6, and 9 days, and cAMP content in three tissues--digestive gland, gills and mantle-gonad complex--was estimated. The results showed significantly increased levels of cAMP in all tissues at all time points tested. In support of our results, cAMP levels were positively correlated with the established metal biomarker, metallothionein. Therefore, we could suggest that mussels exposed to cadmium respond by increasing cAMP content in digestive gland, gills and mantle-gonad complex, thus indicating that cAMP could constitute a promising biomarker of exposure to cadmium.
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