Immunocompetence of marginally nourished women on hormonal contraceptives
1987
Majumder, M.S.I. | Mohiduzzaman, M. | Ahmad, K.
Extract: The objective of the study was to assess the effect of the injectable progestogenic contraceptives on immune status of marginally nourished women belonging to lower middle class. Fifty women were studied; thirty of them were on either medroxyprogesterone acetate or norethisterone enantate and the rest were having no measure of contraception. The number of total T cells in the women on contraceptives was unaltered compared to control women, but phytohaemagglutinin-induced lymphocyte transformation of the same women was depressed significantly (P less than 0.001). The results suggest that the injectable contraceptives which contain steroidal agents may impair cell-mediated immune response in marginally nourished women.(author)
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