Hypertension and diet: Multiple regression analysis in a Japanese farming community | Hypertension and diet: Multiple regression analysis in a Japanese farming community. [letter]
1981
Yamori, Yukio | Kihara, Masahiro | Nara, Yasuo | Ohtaka, Michiya | Horie, Ryoichi | Tsunematsu, Tokugoro | Note, Sinya
An epidemiological study of 1120 inhabitants of a Japanese farming village examined whether dietary factors were causative in essential hypertension. Urinary sodium, potassium, urea nitrogen, inorganic sulfate, and creatinine were measured. Significant increases in the prevalence of hypertension and in mean arterial blood pressure were observed with increasing urinary sodium:potassium ratio in 70 to 80-year-old villagers. This trend was also seen in other age groups. Multivariate regression analysis indicated significant positive correlations between blood pressure and sodium:creatinine, age, and obesity in all subjects. Inverse correlations between blood pressure and potassium:creatinine or sulfate:urea nitrogen (an indicator of animal protein intake) were also observed. Thus, in communities where salt intake is high, dietary factors are associated with hypertension.
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