Selenium and Vitamin E Status: Impact on Viral Pathogenicity
2007
Beck, Melinda A.
Selenium (Se), an essential trace element, and vitamin E, a lipid soluble antioxidant, are important mediators for protection against oxidative stress. Recent work has demonstrated that deficiencies in either Se or vitamin E result in increased viral pathogenicity and altered immune responses. Furthermore, deficiencies in either Se or vitamin E results in specific viral mutations, changing relatively benign viruses into virulent ones. Thus, host nutritional status should be considered a driving force for the emergence of new viral strains or newly pathogenic strains of known viruses.
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