Dietary factors in the aetiology of gastrointestinal cancer
1978
Cummings, John H.
Extract: Gastrointestinal cancers, mainly esophageal, gastric, pancreatic and large bowel cancer, account for about 40,000 deaths annually in England and Wales. Nutritional factors have been implicated in the cause of each cancer and probably act by promoting the effect of carcinogenic substances taken in the diet or produced in the gut. Gastric cancer for example may be due to nitrosamine production in the stomach. Large bowel cancer can be related to high fat and meat intakes, whilst a protective role for dietary fiber has been suggested. Dietary factors in the etiology of esophageal cancer differ from one high incidence area to another.
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