Evaluation of the Bioavailability and Health Risks of Cadmium in Potato Using Three In Vitro Methods
2022
He, Xue | Liu, Ke | Li, Wei | Zhang, Jie | Mao, Chun | Feng, Jihong
In this study, PBET (Physiologically Based Extraction Test), IVG (In Vitro Gastrointestinal), and SBRC (Solubility Bioavailability Research Consortium) were used to compare the bioavailability of Cd in 10 potato varieties and evaluate the risks to human health. The results show that the dissolved Cd content in the gastric and small intestine phase under the three methods is IVG > SBRC > PBET. The most bioavailable method in the gastric and small intestine phases is IVG, and the varieties are Weiyu 5 and Weiyu 7. In the gastric phase, Weiyu 7 had the highest availability, at 73.36%, and in the small intestine phase, Weiyu 5 had the highest availability at 67.48%, and compared with SBRC and PBET, the difference reached a significant level; the varieties with higher bioavailability are Weiyu 5 and Weiyu 7, and the lower varieties are Lishu 13 and Lishu 15 among the 10 potato varieties. Three methods were used to assess the human health risk of Cd in potatoes. The HQ values of different varieties were all less than 1. The ADD and HQ values of Cd ingested by adults and children through potato are generally IVG > SBRC > PBET.
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