Separation and enrichment of enantiopure from racemic compounds using magnetic levitation
2014
Yang, Xiaochuan | Wong, Shin Yee | Bwambok, David K. | Atkinson, Manza B. J. | Zhang, Xi | Whitesides, G. M. | Myerson, Allan S.
Crystallization of a solution with high enantiomeric excess can generate a mixture of crystals of the desired enantiomer and the racemic compound. Using a mixture of S-/RS-ibuprofen crystals as a model, we demonstrated that magnetic levitation (MagLev) is a useful technique for analysis, separation and enantioenrichment of chiral/racemic products.
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