Dietary cholesterol and the plasma lipids and lipoproteins in the Tarahumara Indians: A people habituated to a low cholesterol diet after weaning
1982
McMurry, Martha P. | Connor, William E. | Cerqueira, María T.
Extract: Responsiveness of plasma cholesterol levels to dietary cholesterol was studied in 8 Tarahumara Indian men habituated to a low cholesterol diet. Isocaloric cholesterol-free and high cholesterol diets containing 20% fat, 15% protein, and 65% carbohydrate calories were fed to them. Initial plasma cholesterol concentration was 120 mg/dl. After 3 weeks of a cholesterol-free diet, cholesterol levels were 113 mg/dl. The men were then fed a high cholesterol diet (1000) mg/day) which increased mean total plasma cholesterol to 147 mg/dl and increased low-density lipoprotein cholesterol concentration. Tarahumaras, habituated to a low cholesterol diet after weaning, had the typical hypercholesterolemic response to a high cholesterol diet that has been previously observed in subjects whose lifelong diet was high in cholesterol content. (author/ds)
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