Development of Multiplex Genotyping Method of Polymorphic Markers of Genes Associated with Cognitive Abilities
2018
Vagaitseva, K. V. | Bocharova, A. V. | Marusin, A. V. | Kolesnikova, E. A. | Makeeva, O. A. | Stepanov, V. A.
A developed method of multiplex genotyping of polymorphic markers of genes associated with cognitive abilities and neuropsychiatric diseases is based on multilocus PCR and MALDI-TOF mass spectrometry of DNA molecules. The frequencies of 32 single-nucleotide markers localized in 24 genes are analyzed in a sample of elderly people from the Russian population of Tomsk. The data obtained are compared with data for populations from the 1000 Genomes Project.
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